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1

89.45 A Binomial Identity, via Derangements

Leo Chao, Paul DesJarlais and John L. Leonard

Journal:

The Mathematical Gazette

Year:

2005

Language:

english

File:

PDF, 164 KB

english, 2005

2

A novel series of potent and selective small molecule inhibitors of the complement component C1s

Nalin L. Subasinghe, Farah Ali, Carl R. Illig, M. Jonathan Rudolph, Scott Klein, Ehab Khalil, Richard M. Soll, Roger F. Bone, John C. Spurlino, Renee L. DesJarlais, Carl S. Crysler, Maxwell D. Cumming

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 308 KB

english, 2004

3

Enhanced antibody half-life improves in vivo activity

Zalevsky, Jonathan, Chamberlain, Aaron K, Horton, Holly M, Karki, Sher, Leung, Irene W L, Sproule, Thomas J, Lazar, Greg A, Roopenian, Derry C, Desjarlais, John R

Journal:

Nature Biotechnology

Year:

2010

Language:

english

File:

PDF, 247 KB

english, 2010

4

Rational design and engineering of therapeutic proteins

Shannon A. Marshall, Greg A. Lazar, Arthur J. Chirino, John R. Desjarlais

Journal:

Drug Discovery Today

Year:

2003

Language:

english

File:

PDF, 118 KB

english, 2003

5

A molecular immunology approach to antibody humanization and functional optimization

Greg A. Lazar, John R. Desjarlais, Jonathan Jacinto, Sher Karki, Philip W. Hammond

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 1.14 MB

english, 2007

6

Thoroughly sampling sequence space: Large-scale protein design of structural ensembles

Stefan M. Larson, Jeremy L. England, John R. Desjarlais, Vijay S. Pande

Journal:

Protein Science

Year:

2002

Language:

english

File:

PDF, 251 KB

english, 2002

7

Redirected T Cell Cytotoxicity in Cancer Therapy

Clynes, Raphael A., Desjarlais, John R.

Journal:

Annual Review of Medicine

Year:

2019

Language:

english

File:

PDF, 989 KB

english, 2019

8

New strategies in protein design

John R Desjarlais, Tracy M Handel

Journal:

Current Opinion in Biotechnology

Year:

1995

Language:

english

File:

PDF, 898 KB

english, 1995

9

Computational protein design

Christina M Kraemer-Pecore, Andrew M Wollacott, John R Desjarlais

Journal:

Current Opinion in Chemical Biology

Year:

2001

Language:

english

File:

PDF, 252 KB

english, 2001

10

Structural studies of the engrailed homeodomain

Neil D. Clarke, Charles R. Kissinger, John Desjarlais, Gary L. Gilliland, Carl O. Pabo

Journal:

Protein Science

Year:

1994

Language:

english

File:

PDF, 1.37 MB

english, 1994

11

De novo design of the hydrophobic cores of proteins

John R. Desjarlais, Tracy M. Handel

Journal:

Protein Science

Year:

1995

Language:

english

File:

PDF, 4.35 MB

english, 1995

12

De novo design of the hydrophobic core of ubiquitin

Greg A. Lazar, John R. Desjarlais, Tracy M. Handel

Journal:

Protein Science

Year:

1997

Language:

english

File:

PDF, 4.74 MB

english, 1997

13

From coiled coils to small globular proteins: Design of a native-like three-helix bundle

James W. Bryson, John R. Desjarlais, Tracy M. Handel, William F. Degrado

Journal:

Protein Science

Year:

1998

Language:

english

File:

PDF, 2.18 MB

english, 1998

14

Increased detection of structural templates using alignments of designed sequences

Stefan M. Larson, Amit Garg, John R. Desjarlais, Vijay S. Pande

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2003

Language:

english

File:

PDF, 195 KB

english, 2003

15

Redesigning the DNA-binding specificity of a zinc finger protein: A data base-guided approach

John R. Desjarlais, Jeremy M. Berg

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1992

Language:

english

File:

PDF, 419 KB

english, 1992

16

Discovery, SAR, and X-ray structure of novel biaryl-based dipeptidyl peptidase IV inhibitors

Lei Qiao, Christian A. Baumann, Carl S. Crysler, Nisha S. Ninan, Marta C. Abad, John C. Spurlino, Renee L. DesJarlais, Jukka Kervinen, Mike P. Neeper, Shariff S. Bayoumy, Robyn Williams, Ingrid C. Dec

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 247 KB

english, 2006

17

Dermis-Derived 15-Hydroxy-eicosatertraenoic Acid Inhibits Epidermal 12- Lipoxygenase Activity.

Kragballe, Knud, Pinnamaneni, Gayatri, Desjarlais, Larry, Duell, Elizabeth A., Voorhees, John J.

Journal:

The Journal of Investigative Dermatology

Year:

1986

File:

PDF, 2.35 MB

1986

18

In Vitro Synthesis of 12-Hydroxy-eicosatetraenoic Acid Is Increased in Uninvolved Psoriatic Epidermis.

Kragballe, Knud, Desjarlais, Larry, Duell, Elizabeth A., Voorhees, John J.

Journal:

The Journal of Investigative Dermatology

Year:

1986

File:

PDF, 3.12 MB

1986

19

Solvation energetics and conformational change in EF-hand proteins

Abdessamad Ababou, John R. Desjarlais

Journal:

Protein Science

Year:

2001

Language:

english

File:

PDF, 4.29 MB

english, 2001

20

Rotamer strain as a determinant of protein structural specificity

Greg A. Lazar, Tracy M. Handel, Eric C. Johnson, John R. Desjarlais

Journal:

Protein Science

Year:

1999

Language:

english

File:

PDF, 4.32 MB

english, 1999

21

Prediction of amino acid sequence from structure

Kaushik Raha, Andrew M. Wollacott, Michael J. Italia, John R. Desjarlais

Journal:

Protein Science

Year:

2000

Language:

english

File:

PDF, 3.08 MB

english, 2000

22

Optimizing engagement of the immune system by anti-tumor antibodies: an engineer's perspective

John R. Desjarlais, Greg A. Lazar, Eugene A. Zhukovsky, Seung Y. Chu

Journal:

Drug Discovery Today

Year:

2007

Language:

english

File:

PDF, 651 KB

english, 2007

23

Modulation of antibody effector function

John R. Desjarlais, Greg A. Lazar

Journal:

Experimental Cell Research

Year:

2011

Language:

english

File:

PDF, 632 KB

english, 2011

24

Negative design for improved therapeutic proteins

John R Desjarlais, Greg A Lazar

Journal:

Trends in Biotechnology

Year:

2003

Language:

english

File:

PDF, 73 KB

english, 2003

25

Editorial overview: Computational protein design

John R. Desjarlais, Stephen L. Mayo

Journal:

Current Opinion in Structural Biology

Year:

2002

Language:

english

File:

PDF, 20 KB

english, 2002

26

Designing proteins for therapeutic applications

Greg A Lazar, Shannon A Marshall, Joseph J Plecs, Stephen L Mayo, John R Desjarlais

Journal:

Current Opinion in Structural Biology

Year:

2003

Language:

english

File:

PDF, 167 KB

english, 2003

27

Solution structure and dynamics of a designed hydrophobic core variant of ubiquitin

Eric C Johnson, Greg A Lazar, John R Desjarlais, Tracy M Handel

Journal:

Year:

1999

Language:

english

File:

PDF, 204 KB

english, 1999

28

Side-chain and backbone flexibility in protein core design

John R. Desjarlais, Tracy M. Handel

Journal:

Journal of Molecular Biology

Year:

1999

Language:

english

File:

PDF, 386 KB

english, 1999

29

Virtual interaction profiles of proteins

Andrew M Wollacott, John R Desjarlais

Journal:

Journal of Molecular Biology

Year:

2001

Language:

english

File:

PDF, 898 KB

english, 2001

30

Suppression of mast cell degranulation through a dual-targeting tandem IgE–IgG Fc domain biologic engineered to bind with high affinity to FcγRIIb

Saso Cemerski, Seung Y. Chu, Gregory L. Moore, Umesh S. Muchhal, John R. Desjarlais, David E. Szymkowski

Journal:

Immunology Letters

Year:

2012

Language:

english

File:

PDF, 1.35 MB

english, 2012

31

Engineering Fully Human Monoclonal Antibodies from Murine Variable Regions

Matthew J. Bernett, Sher Karki, Gregory L. Moore, Irene W.L. Leung, Hsing Chen, Erik Pong, Duc-Hanh T. Nguyen, Jonathan Jacinto, Jonathan Zalevsky, Umesh S. Muchhal, John R. Desjarlais, Greg A. Lazar

Journal:

Journal of Molecular Biology

Year:

2010

Language:

english

File:

PDF, 1.18 MB

english, 2010

32

Inhibition of B cell receptor-mediated activation of primary human B cells by coengagement of CD19 and FcγRIIb with Fc-engineered antibodies

Seung Y. Chu, Igor Vostiar, Sher Karki, Gregory L. Moore, Greg A. Lazar, Erik Pong, Patrick F. Joyce, David E. Szymkowski, John R. Desjarlais

Journal:

Molecular Immunology

Year:

2008

Language:

english

File:

PDF, 558 KB

english, 2008

33

Computer search algorithms in protein modification and design

John R Desjarlais, Neil D Clarke

Journal:

Current Opinion in Structural Biology

Year:

1998

Language:

english

File:

PDF, 501 KB

english, 1998

34

A de novo redesign of the WW domain

Christina M. Kraemer-Pecore, Juliette T.J. Lecomte, John R. Desjarlais

Journal:

Protein Science

Year:

2003

Language:

english

File:

PDF, 322 KB

english, 2003

35

Suppression of Rheumatoid Arthritis B Cells by XmAb5871, an Anti-CD19 Antibody That Coengages B Cell Antigen Receptor Complex and Fcγ Receptor IIb Inhibitory Receptor

Chu, Seung Y., Yeter, Karen, Kotha, Roshan, Pong, Erik, Miranda, Yvonne, Phung, Sheryl, Chen, Hsing, Lee, Sung-Hyung, Leung, Irene, Bonzon, Christine, Desjarlais, John R., Stohl, William, Szymkowski,

Journal:

Arthritis & Rheumatology

Year:

2014

Language:

english

File:

PDF, 1.29 MB

english, 2014

36

Long-Range Effects on Calcium Binding and Conformational Change in the N-Domain of Calmodulin †

Ababou, Abdessamad, Shenvi, Ryan A., Desjarlais, John R.

Journal:

Year:

2001

Language:

english

File:

PDF, 130 KB

english, 2001

37

On the nature of poly(chlorotrifluoroethylene) composite electrode surfaces

Petersen, Steven L., Weisshaar, Duane E., Tallman, Dennis E., Schulze, Roland K., Evans, John F., DesJarlais, Scott E., Engstrom, Royce C.

Journal:

Analytical Chemistry

Year:

1988

Language:

english

File:

PDF, 2.95 MB

english, 1988

38

Immune suppression in cynomolgus monkeys by XPro9523

Bernett, Matthew J., Chu, Seung Y., Leung, Irene, Moore, Gregory L., Lee, Sung-Hyung, Pong, Erik, Chen, Hsing, Phung, Sheryl, Muchhal, Umesh S., Horton, Holly M., Lazar, Greg A., Desjarlais, John R, S

Journal:

Year:

2013

Language:

english

File:

PDF, 2.20 MB

english, 2013

39

Increasing FcγRIIa affinity of an FcγRIII-optimized anti-EGFR antibody restores neutrophil-mediated cytotoxicity

Derer, Stefanie, Glorius, Pia, Schlaeth, Martin, Lohse, Stefan, Klausz, Katja, Muchhal, Umesh, Desjarlais, John R, Humpe, Andreas, Valerius, Thomas, Peipp, Matthias

Journal:

Year:

2014

Language:

english

File:

PDF, 3.02 MB

english, 2014

40

Use of a Zinc-Finger Consensus Sequence Framework and Specificity Rules to Design Specific DNA Binding Proteins

John R. Desjarlais and Jeremy M. Berg

Journal:

Proceedings of the National Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 1.07 MB

english, 1993

41

Length-Encoded Multiplex Binding Site Determination: Application to Zinc Finger Proteins

John R. Desjarlais and Jeremy M. Berg

Journal:

Proceedings of the National Academy of Sciences

Year:

1994

Language:

english

File:

PDF, 1.11 MB

english, 1994

42

Toward Rules Relating Zinc Finger Protein Sequences and DNA Binding Site Preferences

John R. Desjarlais and Jeremy M. Berg

Journal:

Proceedings of the National Academy of Sciences

Year:

1992

Language:

english

File:

PDF, 1.01 MB

english, 1992

43

[American Thoracic Society American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado - ()] C21. NEW TARGETS FOR ASTHMA THERAPY - Suppression Of IgE Production By XmAb7195, An Fc-Engineered Antibody That Specifically Coengages Inhibitory Receptor Fc?RIIb With IgE-BCR

Chu, Seung Y., Horton, Holly M., Chen, Hsing, Karki, Sher, Leung, Irene, Szymkowski, David E., Desjarlais, John R.

Year:

2011

Language:

english

File:

PDF, 18 KB

english, 2011

44

Development and thermal performance verification of composite insulation boards containing foam-encapsulated vacuum insulation panels

Biswas, Kaushik, Desjarlais, Andre, Smith, Douglas, Letts, John, Yao, Jennifer, Jiang, Timothy

Journal:

Year:

2018

Language:

english

File:

PDF, 3.68 MB

english, 2018

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